• Users Online: 650
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2019  |  Volume : 6  |  Issue : 4  |  Page : 393-398

Intrathecal atropine versus intravenous metoclopramide for prevention of nausea and vomiting during cesarean section under spinal anesthesia


1 Department of Anesthesiology and Intensive Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt
2 Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Correspondence Address:
MD Tamer El Metwally Farahat
Anesthesiology and Intensive Care, Faculty of Medicine, Mansoura University, Mansoura
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/roaic.roaic_95_18

Rights and Permissions

Background One of the most unpleasant sensation is the occurrence of intraoperative episodes of nausea and vomiting in mothers undergoing cesarean section (CS) under spinal anesthesia. Objective The aim of the present study was to compare the use of prophylactic low-dose atropine in comparison with the effect of metoclopramide for prevention of perioperative nausea and vomiting in mothers undergoing CS under spinal anesthesia. Patients and methods The present study was conducted in 60 full-term mothers of American Society of Anesthesiology Grade I and II, with age between 20 and 35 years with uncomplicated pregnancies. Patients were allocated into two equal groups. Atropine group (group A) included 30 patients who received intrathecal study solution which is a mixture of 2.5 ml of 0.5% hyperbaric bupivacaine, 25 μg fentanyl, and 100 μg of a 1 mg/ml of free atropine sulfate. Metoclopramide group (group M) included 30 patients who received intravenous solution of metoclopramide 10 mg in 2 ml in addition to intrathecal study solution (2.5 ml of 0.5 hyperbaric bupivacaine, 25 μg fentanyl and 100 μg of preservative-free saline 0.9% as a placebo) which was given after spinal anesthesia and before the start of surgical incision. The number of episodes of nausea and vomiting were recorded, and also any other adverse effects were recorded. Results The incidence of intraoperative nausea and vomiting (IONV) and late nausea score were significantly decreased in group A compared with group M (P<0.05), and nearly equal incidence in early onset of nausea in both groups. No differences were noted in terms of postoperative pain or hypotensive episodes. Conclusion Intrathecal atropine can be safely used to decrease intraoperative nausea and vomiting for mothers undergoing CS under spinal anesthesia.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed315    
    Printed42    
    Emailed0    
    PDF Downloaded74    
    Comments [Add]    

Recommend this journal