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ORIGINAL ARTICLE
Year : 2017  |  Volume : 4  |  Issue : 2  |  Page : 70-76

Periarticular infiltration of bupivacaine versus levobupivacaine in postoperative analgesia in patients undergoing total knee arthroplasty


Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Heba M Fathi
Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Zagazig University, Zagazig, 44519
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/roaic.roaic_118_16

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Introduction Pain control is the key in patient’s recovery after arthroplasty. We compared periarticular bupivacaine with levobupivacaine in postoperative analgesia after total knee arthroplasty in this randomized double-blinded study. Patients and Methods Totally, 44 patients were randomly distributed to two equal groups. The L group received periarticular 150 mg levobupivacaine HCl, 0.25% concentration+0.3 mg of adrenaline (1/200 000 concentration) diluted in normal saline to be 60 ml. The B group received periarticular 150 mg bupivacaine HCl, 0.25% concentration+0.3 mg of adrenaline (1/200 000 concentration) diluted in normal saline to be 60 ml. The primary outcomes were the quality of analgesia during 48 h postoperatively, using a visual analog scale score at 6, 12, 18, 24, 36, and 48 h postoperatively and cumulative opioid consumption at 24 and 48 h postoperatively. The secondary outcomes were the functional recovery of the knee and postoperative adverse effects. Result There was no significant difference between the two groups as regards preoperative data. Pain control was comparable in the two groups. No significant complication was observed. There was good functional recovery in both groups with a higher mean degree of knee maximal flexion in the B group. Conclusion Periarticular levobupivacaine and bupivacaine have comparable analgesic effect in patients undergoing total knee arthroplasty.


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