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ORIGINAL ARTICLE
Year : 2017  |  Volume : 4  |  Issue : 2  |  Page : 65-69

Comparison between intrathecal nalbuphine and intrathecal pethidine in preventing postspinal shivering after knee arthroscopy


Department of Anaesthesia and Intensive Care, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Eslam N Nada
Department of Anaesthesia and Intensive Care, Faculty of Medicine, Zagazig University, Flat 702, Moahada Street, El Hedaya Tower 1, El Sharkia, Zagazig - 44519
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/roaic.roaic_101_16

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Background Postspinal shivering is an annoying problem that can lead to many complications. The aim of the present study was to compare the effect of intrathecal nalbuphine with intrathecal pethidine in preventing postspinal shivering in patients undergoing knee arthroscopy. Patients and methods For this randomized study, we included 100 patients (American Society of Anesthesiologists physical status I or II) who were candidates for knee arthroscopy under spinal anesthesia. Participants were divided into two groups: group P (pethidine group, n=50) received 2.5 ml of 0.5% bupivacaine with 25-mg pethidine (total 3 ml) intrathecally, and group N (nalbuphine group, n=50) received 2.5 ml of 0.5% bupivacaine with 0.4-mg nalbuphine (total 3 ml) intrathecally. After establishment of standard monitoring, insertion of venous catheter, and applying the crystalloid infusion warmed to 37°C, intravenous atropine 0.6 mg was administered to all patients. Next, intrathecal block was performed at the L4–L5 level. All patients were operated in the same operating room at a temperature of 23°C. Mean arterial blood pressure, heart rate, arterial oxygen saturation, core (tympanic) temperature, incidence and severity of shivering, and incidence of complications were recorded at baseline, immediately after administration, and then every 5 min until end of surgery. Results Hemodynamic parameters, oxygen saturation, and core temperature were comparable between the two groups. On the other hand, although incidence and intensity of shivering were lower in group P, there was no significant statistical difference between both groups − nine (18%) patients in group P and 17 (34%) patients in group N (P=0.109). In addition, the incidence of complications (hypotension, nausea, and pruritus) was lower in group P but without any significant statistical difference between the two groups. Conclusion Intrathecal nalbuphine is comparable with intrathecal pethidine in preventing postspinal shivering in patients undergoing knee arthroscopy.


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